My research concern the ways of fighting against the contamination of food by special species of molds (Aspergillus flavus) which produce extremely toxic substances called mycotoxyns. Mycotoxyns are carcinogenic and multi-toxic substances which can be found in food and whose ingestion leads for the consumer to food poisoning or food disorder. The consequences are temporary or long-lasting disorders such as alterations in the liver, the loins, the nerve centres, the blood circulation or the digestive tract. The micotoxyns are neither visible to the naked eye nor detectable through taste. They are detected and quantified in food only through analysis in a laboratory. The contamination of food by mycotoxines is a real problem of public health which draws the attention of many researchers worldwide. The objective of my research consists in isolating ground samples with microorganisms (Actinomycètes) having the capacity to inhibit the growth of these toxic molds (Aspergillus flavus).

I am studying the biomolecules of marine organisms for biological interests of Archipelago of Comoros such as: ascidiums, soft corals, sponges and cyanobacteries. In fact, Comoros has a very vast marine economic exclusive zone in the west of Indian Ocean, but this zone is comparatively misread and unexploited in spite of the recent creation on the island of Mwali of a marine park. I want to initiate a study of the marine biodiversity of Comoros, to assess the potential which represents this biodiversity, to promote and to preserve threatened kinds. To promote this biodiversity and preserve threatened kinds, it is essential to identify species. For that it is important to record their chemical signatures and see if we can characterize new metabolites secondary "bioactive". I also study the different consequences that the influence of factors bio - and biotics – have on the production of the secondary metabolites. This research will be the first appraisal to constitute a point of reference for a possible monitoring and also an indicator of environment modifications.

My research is focused on the study of the patterns and processes of the regeneration and stem cell proliferation in a small group of marine free-living flatworms called polyclads. Despite all the efforts to understand how different organisms in the nature are able to restore or replace body parts such as limbs, tails or even heads, the molecular mechanisms underlying regeneration is still unknown.

It was widely demonstrated that a regular and moderate physical activity reduces the incidence of type 2 diabetes, induces an oxidative muscle remodeling by restoring its oxidative capacities, increasing lipid catabolism and insulin sensibility of muscle. Such muscle remodeling is also obtained by a muscle-specific over-expression or pharmacological activation of a nuclear receptor called Peroxisome Proliferator Activated Receptor β (PPARβ). Indeed, PPARβ has been demonstrated to be involved in many different biological functions such as lipid metabolism, mitochondrial physiology, and determination of skeletal muscle fiber type.